From Mayo Clinic to Urbana-Champaign
By ANNA FLANAGAN
When Gabrielle Dillon joined the Department of Health and Kinesiology in the College of Applied Health Sciences last fall, she was greeted by a familiar face. She and Jack Senefeld, who had joined HK in fall 2023, had briefly overlapped in professional positions at the Mayo Clinic in Rochester, Minnesota.
Senefeld, who’d completed his Ph.D. at Marquette University, ended his five-year stint with Mayo in 2023 as a member of the College of Medicine faculty and an associate consultant in the Department of Anesthesiology and Perioperative Medicine and the Department of Physiology and Biomedical Engineering. Dillon joined the Human Integrative Physiology Lab in Mayo’s Department of Anesthesiology and Perioperative Medicine as a postdoctoral fellow in 2022 after completing her Ph.D. at The Pennsylvania State University. They were in different labs in the same department, but the labs collaborated closely.
Senefeld was happy to join the faculty at Illinois because of its outstanding reputation as a research university.
“There are a lot of great tools here to be a successful scientist, and both the university and the College of Applied Health Sciences are highly regarded,” he said.
When another faculty position opened just a year after his arrival, Senefeld forwarded the announcement to “big names and rising stars” in the field, among them his Mayo colleague Dillon.
“I knew both her Ph.D. mentor and her postdoctoral mentor, and her academic credentials are impeccable,” he said. “So we felt really fortunate when we saw her application in the pile.”
In addition to their professional experience, Dillon and Senefeld share research interests. They were members of a working group at Mayo that examined sex differences and physiology, and each makes a point of addressing women’s health in their work.
Dillon’s research focuses on vascular and cardiovascular physiology.
“I’m currently examining vascular testing across a woman’s lifespan and looking at whether physical activity can combat adverse cardiovascular aging and adverse menopause effects,” she said. She hopes not only to advance knowledge related to women’s cardiovascular health, but also to identify effective physical activity-based interventions to improve cardiovascular health. A secondary line of research examines the relationship between birth control and cardiovascular health in women.
Senefeld’s research seeks to understand and to mitigate the detrimental effects of metabolic disease and aging.
“My research focuses primarily on advancing understanding of non-pharmacological interventions—particularly exercise—for aging and metabolic disease,” he said. “I’m investigating how people with prediabetes perform during exercise, specifically how their skeletal muscle performs.”
Through his research, Senefeld hopes to shed light on why people have difficulty complying with exercise guidelines that are known to slow down the progression of diabetes, particularly in older adults. His research will examine how muscles combat fatigue in that population in hopes of increasing their ability to exercise, and he intends to investigate sex differences in muscle performance.
Senefeld and Dillon agree that Illinois is a great place to do human subjects research.
“The standard barriers to human subjects research have really been eliminated here,” Senefeld said. “We have health centers in the area, wonderful laboratory resources for science and multiple units on campus that can analyze samples. And from a practical standpoint, we have parking right outside the building.”
Dillon adds that the departmental culture fosters a supportive research environment.
“Everyone is excited, motivated and eager to collaborate,” she said. “As a new faculty member, I have found everyone to be extremely helpful. We also have a great dean and department head, both of whom are very encouraging.”
Dillon and Senefeld are equally passionate about their teaching. They’ve attended workshops through the Center for Innovation in Teaching and Learning on campus as well as faculty seminars developed by Amy Woods, associate dean for faculty affairs in AHS, and have applied what they’ve learned to co-developing undergraduate and graduate classes. They also are working with the AHS Office of Online Education and Learning Design to develop more effective ways of reaching digitally oriented students.
The heavy demands on young tenure-track scholars have not dampened their enthusiasm for service to their profession. Senefeld co-directs the Lifetime Fitness Program, an exercise program that offers older individuals in the Urbana-Champaign community exercise classes taught by undergraduate and graduate students in health and kinesiology. Dillon is active in the American Physiological Society, of which both she and Senefeld are members. She has developed webinars and career panels for APS, as well as serving on its awards committee. Both are also members of the American College of Sports Medicine, in which Senefeld was recently named a fellow.
The future is bright for Dillon and Senefeld, who are looking forward to long and productive careers at Illinois. As Senefeld put it, “I think we’re both very fortunate to have landed jobs here, and we’re very pleased to be here.”